Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601169 | 0.71 | LMNA (0.51) | LMNAALDH1A1PTGS1PTGS2 | |
| SCHEMBL10759474 | 0.69 | SMN1; SMN2 (0.59) | LMNAALDH1A1PTGS1PTGS2 | |
| SCHEMBL10759479 | 0.69 | SMN1; SMN2 (0.59) | LMNAALDH1A1PTGS1PTGS2 | |
| SCHEMBL11707419 | 0.68 | LMNA (0.41) | LMNAJAK1ALDH1A1 | |
| SCHEMBL10762213 | 0.68 | TUBB1 (0.49) | LMNAALDH1A1 | |
| SCHEMBL10762217 | 0.68 | TUBB1 (0.49) | LMNAALDH1A1 | |
| SCHEMBL7284849 | 0.68 | LMNA (0.44) | LMNAPTGS1PTGS2 | |
| SCHEMBL10764950 | 0.67 | PTGS1 (0.61) | ALDH1A1PTGS1PTGS2 | |
| SCHEMBL10764953 | 0.67 | PTGS1 (0.61) | ALDH1A1PTGS1PTGS2 | |
| SCHEMBL10760284 | 0.67 | MMP9 (0.51) | ALDH1A1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134698-A1 | PYRIDAZINE-1(6H)-6-OXO COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2023-07-20 | — | — | WO | disclosed |