Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.77 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | IAPP | P10997 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305077 | 0.95 | CDK1 (0.81) | CDK1KAT8IAPPPPARAIGF1R | |
| SCHEMBL304629 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL304974 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL27840244 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL9318508 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL304650 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL305081 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL6882282 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL11421416 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 | |
| SCHEMBL11415237 | 0.93 | CDK1 (0.84) | CDK1KAT8PPARAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228356-C | Norbornene polymerization catalyst system and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2005-11-23 | — | — | CN | claimed |
| CN-1200017-C | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2005-05-04 | — | — | CN | claimed |
| CN-1589136-A | Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups | CUTANIX CORP (US) | 2005-03-02 | — | — | CN | claimed |
| CN-1167720-C | Polymeric catalyst system of norbornaene and its preparing process | 中国科学院化学研究所 | 2004-09-22 | — | — | CN | claimed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | claimed |
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | CUTANIX CORPORATION | 2003-08-21 | — | — | US | claimed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | claimed |
| CN-1390867-A | Polymeric catalyst system of norbornaene and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-15 | — | — | CN | claimed |
| CN-1388140-A | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | claimed |
| CN-1388139-A | Norbornene polymerization catalyst system and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | claimed |
| EP-0721482-B1 | ADHESION PROMOTER FOR PVC COMPOUNDS | DU PONT (US) | 1997-11-05 | — | — | EP | claimed |
| EP-0530904-B1 | A composition comprising a polymer of carbon monoxide and ethylenically unsaturated compounds | SHELL INT RESEARCH (NL) | 1997-03-05 | — | — | EP | claimed |
| US-5219954-A | Improved ductility, flexural stiffness, modulus and tensile strength | SHELL OIL COMPANY (US) | 1993-06-15 | — | — | US | claimed |
| EP-0530904-A1 | A composition comprising a polymer of carbon monoxide and ethylenically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-03-10 | — | — | EP | claimed |
| US-9981901-B2 | IRE-1α inhibitors | FOSUN ORINOVE PHARMATECH, INC. (CN) | 2018-05-29 | — | — | US | disclosed |
| US-20170152206-A1 | IRE-1alpha INHIBITORS | FOSUN ORINOVE PHARMATECH, INC. (CN) | 2017-06-01 | — | — | US | disclosed |
| EP-3150589-A1 | IRE-1A INHIBITORS | MannKind Corporation (US) | 2017-04-05 | — | — | EP | disclosed |
| US-4025490-A | PRESSURE SENSITIVE MANIFOLD SYSTEMS | THE MEAD CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3978037-A | POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3953491-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DT) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | TYR, HRH1, HRH2 | CDK1 4235/4885KAT8 832/4885HPGD 65/4885 |
| US-20170152206-A1 | IRE-1alpha INHIBITORS | XBP1, DDIT3, ERN1 | CDK1 1895/4885KAT8 4101/4885HPGD 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.