Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18373201 | 0.89 | HTR2C (0.40) | PNMTASIC3HTR2CSIGMAR1TDP2 | |
| SCHEMBL31430262 | 0.88 | SLC6A4 (0.40) | PNMTASIC3SLC6A4SIGMAR1TDP2 | |
| SCHEMBL30098011 | 0.83 | PNMT (0.40) | PNMTASIC3HTR2CSLC6A4TDP2 | |
| SCHEMBL15505712 | 0.83 | PNMT (0.40) | PNMTASIC3HTR2CSLC6A4TDP2 | |
| SCHEMBL31394396 | 0.82 | LMNA (0.40) | PNMTASIC3SLC6A4TDP2 | |
| Hydrochloric Acid SCHEMBL19616590 | 0.82 | PNMT (0.39) | PNMTASIC3HTR2CSLC6A4TDP2 | |
| SCHEMBL3745717 | 0.81 | AVPR1A (0.40) | SIGMAR1 | |
| SCHEMBL737193 | 0.81 | DPP4 (0.42) | HTR2CSIGMAR1HTR2A | |
| SCHEMBL1275908 | 0.81 | HTR2C (0.47) | PNMTHTR2CSIGMAR1HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL4985671 | 0.79 | AVPR1A (0.39) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |