Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 12/20 | 0.62 |
| ▸ | BMPR1A | P36894 | 12/20 | 0.62 |
| ▸ | TGFBR1 | P36897 | 12/20 | 0.62 |
| ▸ | ACVRL1 | P37023 | 12/20 | 0.62 |
| ▸ | ACVR1 | Q04771 | 12/20 | 0.62 |
| ▸ | AXL | P30530 | 4/20 | 0.60 |
| ▸ | MERTK | Q12866 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29041996 | 1.00 | BMPR1B (0.62) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508325 | 0.93 | ACVR1 (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29041913 | 0.93 | ACVR1 (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29042028 | 0.86 | ACVR1 (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508297 | 0.86 | ACVR1 (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508357 | 0.86 | AXL (0.59) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508192 | 0.85 | BMPR1B (0.58) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508321 | 0.81 | AXL (0.57) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508373 | 0.81 | BMPR1B (0.70) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19806892 | 0.80 | ACVR1 (0.77) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |