Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.57 |
| ▸ | MERTK | Q12866 | 6/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 14/20 | 0.55 |
| ▸ | BMPR1B | O00238 | 13/20 | 0.55 |
| ▸ | BMPR1A | P36894 | 13/20 | 0.55 |
| ▸ | ACVRL1 | P37023 | 13/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 12/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508357 | 0.87 | AXL (0.59) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL30508325 | 0.85 | ACVR1 (0.67) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL29041913 | 0.85 | ACVR1 (0.67) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL29041996 | 0.81 | BMPR1B (0.62) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL30508231 | 0.81 | BMPR1B (0.62) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL30508192 | 0.79 | BMPR1B (0.58) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL29042028 | 0.79 | ACVR1 (0.67) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL30508297 | 0.79 | ACVR1 (0.67) | AXLMERTKACVR1BMPR1BBMPR1A | |
| SCHEMBL19806892 | 0.79 | ACVR1 (0.77) | ACVR1BMPR1BBMPR1AACVRL1TGFBR1 | |
| SCHEMBL30508265 | 0.75 | AXL (0.58) | AXLMERTKACVR1BMPR1BBMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |