Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 9/20 | 0.42 |
| ▸ | BMPR1A | P36894 | 9/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 9/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 9/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508193 | 0.81 | BMPR1B (0.44) | IRAK4BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL3059096 | 0.81 | SMYD3 (0.55) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30964448 | 0.81 | SMYD3 (0.55) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995122 | 0.79 | BMPR1B (0.62) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995120 | 0.79 | BMPR1B (0.62) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995270 | 0.79 | BMPR1B (0.62) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL22585726 | 0.78 | PIK3C3 (0.49) | HPGDSBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL22558893 | 0.78 | PIK3C3 (0.49) | HPGDSBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL22558810 | 0.76 | CNR2 (0.55) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508263 | 0.76 | PIK3C3 (0.56) | HPGDSBMPR1BBMPR1AACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |