Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17586450 | 0.92 | AVPR1A (0.49) | AVPR1AGPR119ESR2ALKNR1H2 | |
| SCHEMBL29716173 | 0.88 | RORC (0.40) | AVPR1AESR2NR1H2BACE1RORC | |
| SCHEMBL12097232 | 0.88 | RORC (0.40) | AVPR1AESR2NR1H2BACE1RORC | |
| SCHEMBL2159558 | 0.86 | AVPR1A (0.49) | AVPR1AESR2 | |
| SCHEMBL30743086 | 0.86 | NR1H2 (0.56) | AVPR1AGPR119ESR2NR1H2USP2 | |
| SCHEMBL12701623 | 0.81 | AVPR1A (0.50) | AVPR1AGPR119ESR2NR1H2USP2 | |
| SCHEMBL30623466 | 0.81 | AVPR1A (0.50) | AVPR1AGPR119ESR2NR1H2USP2 | |
| SCHEMBL20502778 | 0.80 | RORC (0.41) | AVPR1AESR2NR1H2BACE1RORC | |
| SCHEMBL12748317 | 0.80 | FAAH (0.47) | AVPR1AGPR119ESR2ALKNR1H2 | |
| SCHEMBL5917686 | 0.80 | FAAH (0.56) | GPR119ALKIDO1BACE1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023198114-A1 | ALK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |