Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508240 | 1.00 | PRMT5 (0.40) | PRMT5KDM1AMEN1ALDH1A1MAPT | |
| SCHEMBL30450183 | 0.93 | MEN1 (0.43) | PRMT5KDM1AMEN1ALDH1A1MAPT | |
| SCHEMBL10060682 | 0.93 | MEN1 (0.43) | PRMT5KDM1AMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30508276 | 0.92 | MEN1 (0.42) | PRMT5KDM1AMEN1ALDH1A1MAPT | |
| SCHEMBL13468 | 0.84 | HDAC8 (0.39) | HDAC8GPR119HTR2A | |
| SCHEMBL19703386 | 0.83 | MEN1 (0.42) | PRMT5KDM1AMEN1ALDH1A1MAPT | |
| SCHEMBL31757809 | 0.83 | MEN1 (0.42) | PRMT5KDM1AMEN1ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL26683826 | 0.81 | HDAC8 (0.41) | HDAC8GPR119HTR2A | |
| SCHEMBL25045382 | 0.81 | HTR7 (0.39) | HDAC8GPR119HTR2A | |
| SCHEMBL17678127 | 0.81 | PDE9A (0.38) | HDAC8GPR119HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |