SCHEMBL30508352

SCHEMBL30508352

CC(=O)Nc1ccc([N+](=O)[O-])cc1C(F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
MEN1 O00255 5/20 0.57
KMT2A Q03164 5/20 0.57
LMNA P02545 3/20 0.57
MAPT P10636 6/20 0.56
HTT P42858 6/20 0.56
MAPK1 P28482 1/20 0.56
RORC P51449 1/20 0.55
GAA P10253 1/20 0.55
POLB P06746 1/20 0.53
TP53 P04637 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
CYP19A1 P11511 1/20 0.50
PKM P14618 3/20 0.49
PDK1 Q15118 1/20 0.47
PDK2 Q15119 1/20 0.47
PDK3 Q15120 1/20 0.47
PDK4 Q16654 1/20 0.47
EPHX1 P07099 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6811979 1.00 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL11009493 0.88 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL4959345 0.87 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL4959353 0.87 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL31125083 0.87 SMN1; SMN2 (0.51) ALDH1A1MEN1KMT2AMAPTHTT
SCHEMBL3544173 0.87 SMN1; SMN2 (0.51) ALDH1A1MEN1KMT2AMAPTHTT
SCHEMBL9834299 0.85 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL7073743 0.85 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL26416850 0.84 ALDH1A1 (0.67) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL9869867 0.83 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478180-B Fluorescent macrocycle and application thereof in nitroaromatic compound monitoring 南通大学 2024-03-19 CN claimed
CN-116478180-A Fluorescent macrocycle and application thereof in nitroaromatic compound monitoring 南通大学 2023-07-25 CN claimed
CN-116478180-B Fluorescent macrocycle and application thereof in nitroaromatic compound monitoring 南通大学 2024-03-19 CN disclosed
CN-116478180-A Fluorescent macrocycle and application thereof in nitroaromatic compound monitoring 南通大学 2023-07-25 CN disclosed