Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | HTT | P42858 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959353 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL11009493 | 0.89 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL7073743 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL9834299 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL6811979 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL30508352 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL26416850 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL9869867 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL22734230 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL27470288 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094909-A2 | QUINAZOLINONE AND FUSED PYRIMIDINONE COMPOUNDS AND THEIR USE IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-08-07 | — | — | WO | disclosed |