Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 18/20 | 0.65 |
| ▸ | BMPR1A | P36894 | 18/20 | 0.65 |
| ▸ | TGFBR1 | P36897 | 18/20 | 0.65 |
| ▸ | ACVRL1 | P37023 | 18/20 | 0.65 |
| ▸ | ACVR1 | Q04771 | 18/20 | 0.65 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.58 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29042005 | 1.00 | BMPR1B (0.65) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29041913 | 0.81 | ACVR1 (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508325 | 0.81 | ACVR1 (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19807004 | 0.79 | BMPR1B (1.00) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29370273 | 0.79 | BMPR1B (1.00) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508412 | 0.78 | BMPR1B (0.82) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29042031 | 0.78 | BMPR1B (0.82) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508355 | 0.77 | BMPR1B (0.66) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508253 | 0.77 | BMPR1B (0.66) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29042037 | 0.77 | BMPR1B (0.66) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |