SCHEMBL305086

SCHEMBL305086

C=C[SiH](Cc1ccccc1)O[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
MAOB P27338 1/20 0.33
CALM1 P0DP23 1/20 0.32
IDO1 P14902 2/20 0.31
AGXT P21549 1/20 0.30
ALDH1A1 P00352 2/20 0.30
TP53 P04637 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9127529 0.84
SCHEMBL28971498 0.83 TSHR (0.36) TSHRMAOBCALM1IDO1AGXT
SCHEMBL296249 0.80 LTA4H (0.35) TSHRMAOBCALM1IDO1ALDH1A1
SCHEMBL5135539 0.78 KMT2A (0.32) TSHRMAOBCALM1IDO1
SCHEMBL296871 0.77 TP53 (0.37) TSHRMAOBCALM1TP53
SCHEMBL28693788 0.76 TSHR (0.36) TSHRMAOBALDH1A1TP53TRPA1
SCHEMBL4355746 0.72 TSHR (0.46) TSHRMAOBCALM1IDO1AGXT
SCHEMBL5968611 0.72 MAOB (0.40) TSHRMAOBCALM1IDO1ALDH1A1
SCHEMBL1440051 0.72 IDO1 (0.42) TSHRMAOBCALM1IDO1ALDH1A1
Fluoride SCHEMBL27912819 0.70 IDO1 (0.40) TSHRMAOBCALM1IDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024184291-A1 COSMETIC TREATMENT PROCESS COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING AT LEAST ONE VINYL SILICONE, AT LEAST ONE MERCAPTO SILICONE AND AT LEAST ONE LIQUID FATTY SUBSTANCE L'OREAL (FR) 2024-09-12 WO claimed
US-5434214-A Hydrosilation reaction between polysiloxanes, triallyl isocyanurate, diallyl maleate LOCTITE CORPORATION (US) 1995-07-18 US claimed
CN-115279855-B Protective cover member and member supply sheet 日东电工株式会社 2025-02-21 CN disclosed
CN-118647651-A Compositions and methods for compatibilizing polyolefins 落基科技股份有限公司 2024-09-13 CN disclosed
WO-2024184291-A1 COSMETIC TREATMENT PROCESS COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING AT LEAST ONE VINYL SILICONE, AT LEAST ONE MERCAPTO SILICONE AND AT LEAST ONE LIQUID FATTY SUBSTANCE L'OREAL (FR) 2024-09-12 WO disclosed
WO-2024138379-A1 USE OF COATING SYSTEM COMPRISING ACRYLIC PRE-COAT AND SILICONE TOP-COAT IN A PAPER-BASED FOOD CONTAINER AND THE PAPER-BASED FOOD CONTAINER COATED WITH THE COATING SYSTEM ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2024-07-04 WO disclosed
US-20230235206-A1 SILICONE-BASED ADHESIVE AND ADHESIVE TAPE NITTO DENKO CORPORATION (JP) 2023-07-27 US disclosed
EP-4180496-A1 SILICONE-BASED ADHESIVE AND ADHESIVE TAPE NITTO DENKO CORPORATION (JP) 2023-05-17 EP disclosed
US-20230108896-A1 PROTECTIVE COVER MEMBER AND MEMBER SUPPLYING SHEET NITTO DENKO CORPORATION (JP) 2023-04-06 US disclosed
CN-115803414-A Silicone adhesive and adhesive tape 日东电工株式会社 2023-03-14 CN disclosed
CN-115279855-A Protective cover member and member supply sheet 日东电工株式会社 2022-11-01 CN disclosed
US-4741966-A Organopolysiloxane composition curable by hydrosilylation containing platinum/triene complexes RHONE-POULENC SPECIALTIES CHIMIQUES (FR) 1988-05-03 US disclosed
US-4699813-A FROMA PLATINUM HALIDE, ALKALI OR ALKALINE EARTH METAL CARBONATE, AND ALKENYL CYCLOHEXENE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-10-13 US disclosed
US-4687870-A Platinum/triene complexes useful for hydrosilylation catalysis RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-08-18 US disclosed
EP-0091291-B1 ROOM TEMPERATURE STABLE, HEAT ACTIVATED ORGANOPOLYSILOXANE COMPOSITIONS Toray Silicone Company Limited (JP) 1987-05-13 EP disclosed
EP-0188978-A1 Platinum-triene complex as a hydrosilylation catalyst and a process for its preparation RHONE-POULENC CHIMIE (FR) 1986-07-30 EP disclosed
US-4465818-A Room temperature stable, heat activated organopolysiloxane compositions TORAY SILICONE COMPANY, LTD. (JP) 1984-08-14 US disclosed
EP-0091291-A2 Room temperature stable, heat activated organopolysiloxane compositions Toray Silicone Company Limited (JP) 1983-10-12 EP disclosed
US-3983298-A Polyorganosiloxane pressure sensitive adhesives and articles therefrom DOW CORNING CORPORATION (US) 1976-09-28 US disclosed
US-3974122-A Heat-curable silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JA) 1976-08-10 US disclosed