Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321859 | 1.00 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3F2RL3 | |
| SCHEMBL25319198 | 0.80 | F2RL3 (0.38) | SLC6A2SLC6A4SLC6A3F2RL3 | |
| SCHEMBL22042661 | 0.77 | SMN1; SMN2 (0.33) | F2RL3 | |
| SCHEMBL31092688 | 0.77 | SMN1; SMN2 (0.33) | F2RL3 | |
| SCHEMBL31214293 | 0.74 | KMO (0.33) | — | |
| SCHEMBL14123466 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL31214230 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL667990 | 0.68 | ALDH1A1 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30284393 | 0.68 | ALDH1A1 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1149410 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466258-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| CN-118591534-A | Novel benzimidazole pyridine derivatives | 豪夫迈·罗氏有限公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |