Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | DAO | P14920 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003423 | 1.00 | ALOX5 (0.54) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL10821646 | 0.85 | ALOX5 (0.52) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL15416243 | 0.82 | KDM4E (0.55) | ALOX5KDM4EDAOMAPTHPGD | |
| Alanine SCHEMBL28826582 | 0.82 | ALOX5 (0.57) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL25275820 | 0.81 | ALOX5 (0.59) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL9868223 | 0.81 | KDM4E (0.53) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL11162644 | 0.81 | ALOX5 (0.46) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL1767751 | 0.79 | ALOX5 (0.57) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL29875597 | 0.79 | ALOX5 (0.57) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL27831047 | 0.79 | ALOX5 (0.50) | ALOX5KDM4EDAOMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119584979-A | Use of kinin or derivatives thereof for the treatment of hypertension, prevention or treatment of complications of hypertension | 江苏众红生物工程创药研究院有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119367503-A | Use of kinin or derivatives thereof for the treatment of hypertension, prevention or treatment of complications of hypertension | 江苏众红生物工程创药研究院有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-118541172-A | Use of kinin or derivatives thereof for the treatment of VCI, PSCI or CSVD | 江苏众红生物工程创药研究院有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-116554267-A | Polyethylene glycol modified kinin or variant thereof and pharmaceutical use thereof | 江苏众红生物工程创药研究院有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116549599-A | Use of kinin and its derivatives in the treatment of VCI, PSCI or CSVD | 江苏众红生物工程创药研究院有限公司 | 2023-08-08 | — | — | CN | disclosed |