Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15416243 | 0.84 | KDM4E (0.55) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL29875597 | 0.81 | ALOX5 (0.57) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL1767751 | 0.81 | ALOX5 (0.57) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL30508997 | 0.81 | ALOX5 (0.54) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL8003423 | 0.81 | ALOX5 (0.54) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL28337512 | 0.79 | ALOX5 (0.50) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL8573988 | 0.79 | ALOX5 (0.50) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL2661862 | 0.78 | KDM4E (0.49) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL21686469 | 0.78 | ALOX5 (0.55) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL24358497 | 0.77 | ALOX5 (0.50) | KDM4EDAOMAPTHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2425356-B1 | COMPUTER IMPLEMENTED SYSTEM AND METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT | CINCINNATI CHILDRENS HOSPITAL MEDICAL CENTER (US) | 2019-03-13 | — | — | EP | claimed |
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | disclosed |