SCHEMBL30512493

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O

nearest known ligand 0.54

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	14/20	0.54

▸	CALCR	P30988	14/20	0.54

▸	MAPK8	P45983	1/20	0.49

▸	MAPK9	P45984	1/20	0.49

▸	MAPK10	P53779	1/20	0.49

▸	EP300	Q09472	1/20	0.47

▸	HIF1A	Q16665	1/20	0.47

▸	KEAP1	Q14145	1/20	0.46

▸	CXCR4	P61073	1/20	0.46

▸	NMUR2	Q9GZQ4	1/20	0.46

▸	NMUR1	Q9HB89	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29783025	0.90	RAMP3 (0.53)	RAMP3CALCRCXCR4NMUR2NMUR1
SCHEMBL31467773	0.89	RAMP3 (0.51)	RAMP3CALCRCXCR4
SCHEMBL29782941	0.87	CXCR4 (0.53)	RAMP3CALCRCXCR4
SCHEMBL29905998	0.86	KEAP1 (0.45)	RAMP3CALCRKEAP1CXCR4
SCHEMBL30868635	0.86	KEAP1 (0.45)	RAMP3CALCRKEAP1CXCR4
SCHEMBL30957282	0.86	EPHA2 (0.49)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL30868640	0.86	NMUR2 (0.44)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL30868651	0.85	KEAP1 (0.44)	RAMP3CALCRKEAP1CXCR4NMUR2
SCHEMBL30437447	0.85	RAMP3 (0.58)	RAMP3CALCRCXCR4
SCHEMBL29783021	0.84	OPRM1 (0.54)	RAMP3CALCRKEAP1NMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116490215-A	Targeted mediated endocytic drug delivery	CRM医疗有限公司	2023-07-25	—	—	CN	disclosed