Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16840300 | 0.86 | HPGD (0.69) | HPGDALDH1A1HTTGAAPKM | |
| SCHEMBL16840366 | 0.85 | TAS1R3 (0.58) | HPGDCYP3A4ALDH1A1HTTGAA | |
| SCHEMBL16840118 | 0.81 | HPGD (0.56) | HPGDALDH1A1HTTGAAPKM | |
| SCHEMBL30513016 | 0.81 | HPGD (0.72) | HPGDCYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL2267405 | 0.77 | ALDH1A1 (0.52) | HPGDALDH1A1HTTGAAPKM | |
| SCHEMBL23985899 | 0.76 | TAS1R3 (0.71) | HPGDALDH1A1HTTGAAPKM | |
| SCHEMBL3606953 | 0.76 | SMN1; SMN2 (0.60) | ALDH1A1PKMKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL30305533 | 0.76 | TAS1R3 (0.71) | HPGDALDH1A1HTTGAAPKM | |
| SCHEMBL16840365 | 0.76 | TAS1R3 (0.63) | HPGDALDH1A1HTTGAAPKM | |
| SCHEMBL6428110 | 0.75 | MEN1 (0.59) | HPGDALDH1A1HTTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |