Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TDP2 | O95551 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22782798 | 0.80 | HTT (0.58) | HTTTDP2HPGDHSD17B10GFER | |
| SCHEMBL21768055 | 0.80 | HTT (0.58) | HTTHPGDHSD17B10GFERALDH1A1 | |
| SCHEMBL21768027 | 0.78 | HTT (0.55) | HTTTDP2HPGDHSD17B10GFER | |
| SCHEMBL12302510 | 0.77 | TDP2 (0.48) | HTTTDP2PARP10PARP11BRD4 | |
| SCHEMBL31394401 | 0.77 | BRD4 (0.46) | HTTTDP2HPGDHSD17B10GFER | |
| SCHEMBL4842012 | 0.75 | NPSR1 (0.62) | HTTTDP2HPGDHSD17B10GFER | |
| SCHEMBL29964356 | 0.75 | NPSR1 (0.62) | HTTTDP2HPGDHSD17B10GFER | |
| SCHEMBL30016582 | 0.74 | TDP2 (0.48) | HTTTDP2PARP10PARP11ALDH1A1 | |
| SCHEMBL1500161 | 0.74 | TDP2 (0.46) | TDP2PARP10PARP11ALDH1A1BRD4 | |
| SCHEMBL24697708 | 0.73 | MGAT2 (0.44) | HTTTDP2HPGDHSD17B10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |