Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29964356 | 1.00 | NPSR1 (0.62) | NPSR1ALDH1A1POLBHPGDGFER | |
| SCHEMBL1233069 | 0.81 | ALDH1A1 (0.50) | NPSR1ALDH1A1POLBHPGDGFER | |
| SCHEMBL10323613 | 0.78 | CA12 (0.53) | NPSR1ALDH1A1POLBHPGDHTT | |
| SCHEMBL15910500 | 0.76 | GAA (0.60) | NPSR1ALDH1A1POLBHPGDGFER | |
| SCHEMBL21768055 | 0.75 | HTT (0.58) | ALDH1A1HPGDGFERHSD17B10HTT | |
| SCHEMBL22782798 | 0.75 | HTT (0.58) | NPSR1ALDH1A1HPGDGFERHSD17B10 | |
| SCHEMBL30512977 | 0.75 | HTT (0.58) | NPSR1ALDH1A1HPGDGFERHSD17B10 | |
| SCHEMBL11663391 | 0.74 | ALDH1A1 (0.54) | NPSR1ALDH1A1POLBHPGDGFER | |
| SCHEMBL9542535 | 0.74 | ALDH1A1 (0.90) | NPSR1ALDH1A1POLBHSD17B10HTT | |
| SCHEMBL21768027 | 0.73 | HTT (0.55) | ALDH1A1HPGDGFERHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848364-B1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| EP-3929197-B1 | INTERMEDIATES FOR THE SYNTHESIS OF MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2024-03-06 | — | — | EP | disclosed |
| US-20230350294-A1 | Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-11768434-B2 | Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11768434-B2 | Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-26 | — | — | US | disclosed |
| EP-3334736-B1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-28 | — | — | EP | disclosed |
| EP-3683213-B1 | INTERMEDIATE FOR THE PREPARATION OF MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-10-12 | — | — | EP | disclosed |
| EP-3929197-A1 | INTERMEDIATES FOR THE SYNTHESIS OF MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-29 | — | — | EP | disclosed |
| CN-109890208-B | Fungicidal compositions | 先正达参股股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-110300521-B | Fungicidal compositions | 先正达参股股份有限公司 | 2021-10-15 | — | — | CN | disclosed |
| EP-3334736-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | Syngenta Participations AG (CH) | 2018-06-20 | — | — | EP | disclosed |
| WO-2018060039-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-05 | — | — | WO | disclosed |
| US-20180079740-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| EP-3274343-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | Syngenta Participations AG (CH) | 2018-01-31 | — | — | EP | disclosed |
| WO-2017025510-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-16 | — | — | WO | disclosed |
| WO-2016156085-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |
| US-7378428-B2 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |
| US-6956033-B2 | 3,4-dihydroisoquinoline derivative compound and a pharmaceutical agent comprising it as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-18 | — | — | US | disclosed |
| US-20050222138-A1 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| US-20040077643-A1 | 3,4 Dihydroisoquinoline derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079740-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | MSR1, MANBA, ALG1 | NPSR1 1229/4885ALDH1A1 2030/4885POLB 1494/4885 |
| US-20040077643-A1 | 3,4 Dihydroisoquinoline derivative compounds and drugs containing these compounds as the active ingredient | CNR1, CNR2, TRPV1 | NPSR1 185/4885ALDH1A1 2167/4885POLB 2806/4885 |
| US-20050222138-A1 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | PARK7, MMP8, CDK7 | NPSR1 280/4885ALDH1A1 2636/4885POLB 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.