Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301310 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| SCHEMBL5973721 | 0.79 | MAPT (0.47) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| Iodide SCHEMBL31385461 | 0.78 | MAPT (0.46) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| SCHEMBL6990668 | 0.73 | MAPT (0.52) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| SCHEMBL1253847 | 0.72 | MAPT (0.50) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| SCHEMBL20997818 | 0.72 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| SCHEMBL11127668 | 0.71 | MAP4K4 (0.58) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| SCHEMBL29442167 | 0.71 | MAP4K4 (0.58) | MAPTSMN1; SMN2NPC1RAB9AGFER | |
| SCHEMBL14917440 | 0.71 | CHEK2 (0.49) | CCNCCDK8KDRCHEK2ALDH1A1 | |
| SCHEMBL28803622 | 0.71 | KDR (0.79) | MAPTSMN1; SMN2NPC1RAB9AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592534-B | New compounds | 特殊治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |