Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5973721 | 0.98 | MAPT (0.47) | MAPTNOS3NOS2LMNASMN1; SMN2 | |
| SCHEMBL1165179 | 0.81 | GSK3B (0.47) | MAPTNOS3NOS2LMNAAURKB | |
| SCHEMBL30513239 | 0.78 | MAPT (0.50) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11901650 | 0.78 | MAP4K4 (0.46) | NOS3NOS2LMNANPC1RAB9A | |
| SCHEMBL13730604 | 0.78 | NOS3 (0.52) | MAPTNOS3NOS2LMNANPC1 | |
| SCHEMBL17555671 | 0.78 | CDK2 (0.43) | MAPTNOS3NOS2SMN1; SMN2GFER | |
| SCHEMBL3243063 | 0.77 | KIF11 (0.47) | NOS3NOS2MAP4K4 | |
| SCHEMBL5319523 | 0.75 | NOS2 (0.44) | NOS3NOS2LMNASMN1; SMN2NPC1 | |
| SCHEMBL17565133 | 0.75 | CYP2A6 (0.50) | MAPTLMNASMN1; SMN2CHEK2CYP2D6 | |
| SCHEMBL17555583 | 0.75 | CYP2A6 (0.50) | NOS3NOS2KDRCHEK2IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037215-A | Molecular imprinting hydrogen bond organic framework adsorption material and preparation method and application thereof | 重庆市食品药品检验检测研究院 | 2026-05-15 | — | — | CN | claimed |
| CN-119119501-A | Three-component hydrogen bond organic framework material and preparation method and application thereof | 陕西科技大学 | 2024-12-13 | — | — | CN | claimed |
| CN-122037215-A | Molecular imprinting hydrogen bond organic framework adsorption material and preparation method and application thereof | 重庆市食品药品检验检测研究院 | 2026-05-15 | — | — | CN | disclosed |
| CN-119119501-A | Three-component hydrogen bond organic framework material and preparation method and application thereof | 陕西科技大学 | 2024-12-13 | — | — | CN | disclosed |