Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | PRF1 | P14222 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546902 | 1.00 | MEN1 (0.50) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL8268526 | 0.87 | GRM5 (0.54) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL29746448 | 0.86 | MEN1 (0.49) | MEN1KMT2ADDB1CRBNDRD2 | |
| SCHEMBL3545811 | 0.86 | MEN1 (0.49) | MEN1KMT2ADDB1CRBNDRD2 | |
| SCHEMBL26669939 | 0.84 | MEN1 (0.48) | MEN1KMT2ADDB1CRBNGRM5 | |
| SCHEMBL20455902 | 0.83 | KCNJ1 (0.51) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL5014215 | 0.81 | KCNJ1 (0.42) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL13505919 | 0.80 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL12038178 | 0.78 | MEN1 (0.54) | MEN1KMT2ADDB1CRBNGRM5 | |
| SCHEMBL2386047 | 0.78 | MEN1 (0.54) | MEN1KMT2ADDB1CRBNDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269415-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | Modulus Discovery, Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| CN-116583286-A | Tetrahydrothienopyrimidine sulfonamide compounds | 某久拉斯株式会社 | 2023-08-11 | — | — | CN | disclosed |