SCHEMBL20455902

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21873388	0.86	ALDH1A1 (0.47)	KCNJ1DDB1CRBNALDH1A1MEN1
	SCHEMBL20456055	0.85	GABRA1 (0.44)	KCNJ1DDB1CRBNALDH1A1MEN1
	SCHEMBL3546902	0.83	MEN1 (0.50)	KCNJ1DDB1CRBNALDH1A1MEN1
	SCHEMBL21729751	0.83	CNR2 (0.43)	KCNJ1DDB1CRBNALDH1A1MEN1
	SCHEMBL30514543	0.83	MEN1 (0.50)	KCNJ1DDB1CRBNALDH1A1MEN1
	SCHEMBL19150822	0.78	KCNJ1 (0.43)	KCNJ1ALDH1A1MEN1KMT2AGAA
	SCHEMBL435023	0.77	DDB1 (0.48)	DDB1CRBNALDH1A1MEN1KMT2A
	SCHEMBL21983836	0.75	DDB1 (0.47)	DDB1CRBNMEN1KMT2APRF1
	SCHEMBL8380361	0.75	DDB1 (0.47)	DDB1CRBNALDH1A1MEN1KMT2A
	SCHEMBL13213025	0.75	GABRG2 (0.47)	DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.