Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22432119 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPK10GSK3ARIOK2 | |
| SCHEMBL2563299 | 0.83 | KDM4C (0.46) | ALDH1A1MAPK10GSK3ARIOK2HPGD | |
| SCHEMBL12461245 | 0.83 | SMN1; SMN2 (0.63) | ALDH1A1MAPK10GSK3ARIOK2NPC1 | |
| SCHEMBL15910524 | 0.82 | L3MBTL1 (0.56) | ALDH1A1MAPK10GSK3ARIOK2HPGD | |
| SCHEMBL4302326 | 0.82 | NR3C2 (0.46) | ALDH1A1LMNAMAPK10GSK3ARIOK2 | |
| SCHEMBL1555088 | 0.82 | HPGD (0.54) | ALDH1A1LMNAMAPK10RIOK2HPGD | |
| SCHEMBL26686195 | 0.82 | EGFR (0.46) | ALDH1A1MAPK10GSK3ARIOK2HPGD | |
| SCHEMBL25997635 | 0.82 | NPC1 (0.48) | ALDH1A1MAPK10GSK3ARIOK2HPGD | |
| SCHEMBL15011770 | 0.82 | MAPK10 (0.45) | ALDH1A1LMNAMAPK10GSK3ARIOK2 | |
| SCHEMBL16926556 | 0.81 | JAK2 (0.58) | MAPK10GSK3ARIOK2MAPTNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903526-A | Pyridinylpyridinone compounds | 思普瑞特生物科学公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116891431-A | Pyridinylpyridinone compounds | 思普瑞特生物科学公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-111094244-B | Pyridinylpyridinone compounds | 思普瑞特生物科学公司 | 2023-07-11 | — | — | CN | disclosed |