Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP4 | Q02790 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295440 | 0.96 | FKBP4 (0.53) | FKBP4LMNAKCNH2ALDH1A1TACR1 | |
| SCHEMBL11435718 | 0.90 | NAMPT (0.48) | FKBP4LMNAKCNH2ALDH1A1TACR1 | |
| SCHEMBL29558027 | 0.89 | FKBP4 (0.55) | FKBP4ALDH1A1TACR1 | |
| SCHEMBL14050092 | 0.87 | FKBP4 (0.57) | FKBP4ALDH1A1TACR1TRPV1MEN1 | |
| SCHEMBL10305897 | 0.85 | FKBP4 (0.70) | FKBP4TACR1 | |
| SCHEMBL29361508 | 0.85 | FKBP4 (0.70) | FKBP4TACR1 | |
| SCHEMBL1296384 | 0.85 | LMNA (0.48) | LMNAKCNH2ALDH1A1TACR1TRPV1 | |
| SCHEMBL27824844 | 0.85 | LMNA (0.48) | LMNAKCNH2ALDH1A1TACR1TRPV1 | |
| SCHEMBL29393137 | 0.83 | FKBP4 (0.49) | FKBP4KCNH2ALDH1A1TACR1 | |
| SCHEMBL30610198 | 0.83 | ALDH1A1 (0.50) | FKBP4LMNAALDH1A1NAMPTPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410962-A | Prolyl endopeptidase mutant and application thereof | 四川大学 | 2023-07-11 | — | — | CN | disclosed |