Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 12/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 6/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515943 | 0.84 | SRC (0.37) | KDRMAPTGAASRCLRRK2 | |
| SCHEMBL30515768 | 0.82 | LRRK2 (0.38) | FGFR2FGFR3FGFR1FGFR4MAPT | |
| SCHEMBL31062042 | 0.80 | MAPK13 (0.32) | MAPT | |
| SCHEMBL30515933 | 0.80 | MAPT (0.34) | FGFR2FGFR3KDRFGFR1FGFR4 | |
| SCHEMBL30515914 | 0.79 | MAPT (0.31) | MAPT | |
| SCHEMBL31062036 | 0.78 | — | — | |
| SCHEMBL30515808 | 0.77 | FGFR2 (0.39) | FGFR2FGFR3KDRFGFR1FGFR4 | |
| SCHEMBL30515840 | 0.76 | LRRK2 (0.32) | FGFR2FGFR3KDRMAPTGAA | |
| SCHEMBL15345676 | 0.75 | FGFR2 (0.47) | FGFR2FGFR3KDRFGFR1FGFR4 | |
| SCHEMBL19993623 | 0.75 | PLA2G2A (0.44) | FGFR2FGFR3FGFR1FGFR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514806-A | Biological inhibitor containing acrylketone, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |