Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | GLA | P06280 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | IDO1 | P14902 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | TDO2 | P48775 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | PTGES | O14684 | 4/20 | 0.67 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20211621 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL13350223 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL2062319 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL29930654 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL25797178 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL4794657 | 0.81 | PTGES (0.69) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL31756946 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL13872535 | 0.81 | GAA (0.68) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL28928675 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL28147490 | 0.80 | GAA (0.67) | KDM4EALDH1A1GAAMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | disclosed |