Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20211622 | 1.00 | MEN1 (0.58) | MEN1KMT2ACYP2C9KDM4ECYP3A4 | |
| SCHEMBL30625697 | 0.91 | TP53 (0.55) | MEN1KMT2ACYP2C9KDM4ECYP3A4 | |
| SCHEMBL12192038 | 0.74 | TRPV1 (0.52) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL30516131 | 0.74 | CYP2C9 (1.00) | MEN1KMT2ACYP2C9KDM4ECYP3A4 | |
| SCHEMBL2583091 | 0.74 | CYP2C9 (1.00) | MEN1KMT2ACYP2C9KDM4ECYP3A4 | |
| SCHEMBL7931362 | 0.74 | KMT2A (0.52) | MEN1KMT2ACYP2C9KDM4ECYP1A2 | |
| SCHEMBL15537236 | 0.71 | MEN1 (0.58) | MEN1KMT2ACYP2C9KDM4ECYP3A4 | |
| SCHEMBL10082377 | 0.71 | KDM4E (0.47) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL11564630 | 0.71 | MAOB (0.71) | KDM4ETDP1CYP1A2MAPTMAPK1 | |
| SCHEMBL25149031 | 0.70 | LMNA (1.00) | MEN1KMT2ACYP2C9CYP3A4ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | disclosed |