Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | APOB | P04114 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516134 | 0.91 | MEN1 (0.58) | ALDH1A1LMNAKDM4EGAAPOLB | |
| SCHEMBL20211622 | 0.91 | MEN1 (0.58) | ALDH1A1LMNAKDM4EGAAPOLB | |
| SCHEMBL12192038 | 0.74 | TRPV1 (0.52) | TP53HTTALDH1A1LMNAKDM4E | |
| SCHEMBL30625698 | 0.74 | KDM4E (0.83) | TP53CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7931362 | 0.74 | KMT2A (0.52) | ALDH1A1L3MBTL1KDM4EGAAPOLB | |
| SCHEMBL1017796 | 0.73 | CHRNB2 (1.00) | TP53CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13329267 | 0.71 | LMNA (0.78) | TP53CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10082377 | 0.71 | KDM4E (0.47) | TP53ALDH1A1LMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL29598779 | 0.71 | CHRNB2 (0.96) | TP53CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11564630 | 0.71 | MAOB (0.71) | ALDH1A1LMNAKDM4EGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548022-B1 | COMPOSITIONS FOR MODULATING PD-1 SIGNAL TRANSDUCTION | UNIV RES INST INC AUGUSTA (US) | 2023-11-22 | — | — | EP | claimed |