Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20211618 | 1.00 | KMT2A (1.00) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL669669 | 0.89 | MAPT (0.80) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL19124864 | 0.88 | MAPT (1.00) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL30180507 | 0.85 | KMT2A (0.80) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL19151510 | 0.85 | KMT2A (0.80) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL26649077 | 0.82 | KMT2A (0.70) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL30232549 | 0.81 | KMT2A (0.78) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL19151496 | 0.81 | KMT2A (0.78) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL19151335 | 0.81 | MAPT (0.82) | KMT2AMAPTMAPK1POLBALDH1A1 | |
| SCHEMBL30180657 | 0.81 | MAPT (0.82) | KMT2AMAPTMAPK1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | disclosed |