SCHEMBL669669

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL670281	0.89	USP2 (0.65)	MAPTKMT2AUSP2POLBMAPK1
	SCHEMBL20211618	0.89	KMT2A (1.00)	MAPTKMT2AUSP2POLBMAPK1
	SCHEMBL30516137	0.89	KMT2A (1.00)	MAPTKMT2AUSP2POLBMAPK1
	SCHEMBL26649077	0.88	KMT2A (0.70)	MAPTKMT2AUSP2POLBMAPK1
	SCHEMBL9124370	0.80	DNMT1 (1.00)	MAPTKMT2AUSP2POLBKDM4E
	SCHEMBL24006029	0.80	DNMT1 (0.89)	MAPTKMT2AUSP2POLBMAPK1
	SCHEMBL30287674	0.80	DNMT1 (0.89)	MAPTKMT2AUSP2POLBMAPK1
	Hydrochloric Acid SCHEMBL1881241	0.79	DNMT1 (0.98)	MAPTKMT2AUSP2POLBKDM4E
	SCHEMBL4367899	0.78	ABCG2 (0.67)	MAPTKMT2AUSP2POLBMAPK1
	SCHEMBL24003743	0.78	DNMT1 (0.85)	MAPTKMT2AUSP2POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.