SCHEMBL30516174

SCHEMBL30516174

CC(C)(C[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.50
▸ POLRMT O00411 1/20 0.32
▸ RIPK1 Q13546 3/20 0.31
▸ DOT1L Q8TEK3 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473192 0.87 TMPRSS2 (0.53) TMPRSS2POLRMTRIPK1DOT1L
SCHEMBL30939839 0.86 TMPRSS2 (0.46) TMPRSS2POLRMTRIPK1
SCHEMBL20533524 0.85 TMPRSS2 (0.53) TMPRSS2POLRMT
SCHEMBL25909499 0.85 TMPRSS2 (0.51) TMPRSS2POLRMT
SCHEMBL26094319 0.85 TMPRSS2 (0.51) TMPRSS2POLRMTRIPK1DOT1L
SCHEMBL30939807 0.85 TMPRSS2 (0.44) TMPRSS2POLRMT
SCHEMBL23960046 0.85 TMPRSS2 (0.48) TMPRSS2POLRMTRIPK1
Gs-441524 SCHEMBL23870459 0.84 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL22142944 0.84 TMPRSS2 (0.60) TMPRSS2POLRMT
Gs-441524 SCHEMBL24667691 0.84 TMPRSS2 (0.60) TMPRSS2POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118304315-B Application of nucleoside compound in preparation of respiratory syncytial virus infection resistant related products 深圳安泰维生物医药有限公司 2025-03-25 — — CN disclosed
CN-117599063-B Application of nucleoside compound in preparation of poxvirus related products 深圳安泰维生物医药有限公司 2024-11-15 — — CN disclosed
CN-118304315-A Application of nucleoside compound in preparation of respiratory syncytial virus infection resistant related products 深圳安泰维生物医药有限公司 2024-07-09 — — CN disclosed
CN-118027040-A Nucleoside compound for treating coronavirus infection and application thereof 南方科技大学 2024-05-14 — — CN disclosed
CN-117964624-A Nucleoside compound with effect of treating viral infection and application thereof 南方科技大学 2024-05-03 — — CN disclosed
CN-117777141-A Nucleoside compound for resisting virus infection and application thereof 南方科技大学 2024-03-29 — — CN disclosed
CN-117599063-A Application of nucleoside compound in preparation of poxvirus related products 深圳安泰维生物医药有限公司 2024-02-27 — — CN disclosed
CN-116370479-B Use of compound ATV014 in the preparation of a product for the treatment of novel coronavirus infection 南方科技大学 2024-02-13 — — CN disclosed
CN-113735862-B Nucleoside compound for treating viral infection and application thereof 南方科技大学 2024-02-02 — — CN disclosed
CN-116874490-A Compound ATV014 or pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof 南方科技大学 2023-10-13 — — CN disclosed
CN-116370479-A Use of compound ATV014 in the preparation of a product for the treatment of novel coronavirus infection 南方科技大学 2023-07-04 — — CN disclosed
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