SCHEMBL30516191

SCHEMBL30516191

Pc1ccc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
BACE1 P56817 1/20 0.39
ALDH1A1 P00352 4/20 0.38
ALOX5 P09917 1/20 0.38
HSD17B10 Q99714 2/20 0.37
CYP2A6 P11509 2/20 0.37
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
MAPK1 P28482 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
ESR2 Q92731 1/20 0.34
CTRC Q99895 2/20 0.33
DPP4 P27487 1/20 0.33
HNF4A P41235 1/20 0.33
PDE4B Q07343 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464416 1.00 LMNA (0.40) LMNAMAPTHTTBACE1ALDH1A1
SCHEMBL608536 0.87 ALDH1A1 (0.50) LMNAMAPTHTTBACE1ALDH1A1
Acetic Acid SCHEMBL9279904 0.86 MAPT (0.38) LMNAMAPTHTTBACE1ALOX5
SCHEMBL28710407 0.84 LMNA (0.48) LMNAMAPTHTTBACE1ALDH1A1
SCHEMBL14390391 0.84 LMNA (0.48) LMNAMAPTHTTBACE1ALDH1A1
Biphenyl SCHEMBL28876393 0.84 ALDH1A1 (0.56) LMNAMAPTHTTBACE1ALDH1A1
Water SCHEMBL28835132 0.84 LMNA (0.48) LMNAMAPTHTTBACE1ALDH1A1
Acetic Acid SCHEMBL9279897 0.83 MAPT (0.36) LMNAMAPTHTTBACE1HPGD
SCHEMBL10596052 0.82 CYP2A6 (0.41) LMNAMAPTHTTBACE1ALDH1A1
SCHEMBL10935465 0.82 LMNA (0.42) LMNAMAPTHTTBACE1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115353471-B Organic electrode material of anthroquinone polymer, and preparation method and application thereof 陕西师范大学 2023-12-05 CN claimed
CN-117801107-A Benzazepine derivatives, conjugates containing same and application thereof 上海迪诺医药科技有限公司 2024-04-02 CN disclosed
CN-117222626-A Substituted triazine compounds 安斯泰来制药株式会社 2023-12-12 CN disclosed
CN-116655534-A Synthetic method of Boc-3- (3-pyrazole) -L-alanine 上海吉奉生物科技有限公司 2023-08-29 CN disclosed
CN-111527090-B Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors 拜耳公司 2023-05-26 CN disclosed