SCHEMBL30516197

SCHEMBL30516197

O=c1nc(-c2cccc3ccccc23)[nH]c(=O)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.50
KDM4E B2RXH2 3/20 0.47
ALPL P05186 1/20 0.47
GAA P10253 1/20 0.47
PI4KA P42356 1/20 0.46
PI4K2B Q8TCG2 1/20 0.46
PI4K2A Q9BTU6 1/20 0.46
PI4KB Q9UBF8 1/20 0.46
NOS1 P29475 1/20 0.42
MAPK13 O15264 1/20 0.41
GCGR P47871 1/20 0.41
MAPK12 P53778 1/20 0.41
MAPK11 Q15759 1/20 0.41
MAPK14 Q16539 1/20 0.41
IDO1 P14902 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTPN1 P18031 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28135155 0.75 GUSB (0.69) KDM4EGAAGUSBHPGD
SCHEMBL186872 0.74 PI4KA (0.49) TYMPKDM4EALPLGAAPI4KA
SCHEMBL17829671 0.73 GUSB (0.58) TYMPMAPK14GUSB
SCHEMBL10412916 0.72 BTK (0.59) KDM4EGAACYP1A2CYP2C19POLB
SCHEMBL20362681 0.72 BTK (0.59) KDM4EGAACYP1A2CYP2C19POLB
SCHEMBL24317556 0.72 PI4KA (0.47) TYMPKDM4EALPLGAAPI4KA
SCHEMBL11828539 0.71 PI4KA (0.55) TYMPKDM4EALPLGAAPI4KA
SCHEMBL31677102 0.70 NPC1 (0.66) KDM4EGAAHPGD
SCHEMBL784353 0.70 NPC1 (0.66) KDM4EGAAHPGD
SCHEMBL29825055 0.70 NPC1 (0.66) KDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655549-A Preparation method of polysubstituted 1,3,5-triazine derivative 湖北尚赛光电材料有限公司 2023-08-29 CN disclosed