SCHEMBL784353

SCHEMBL784353

c1ccc2c(-c3nc4ccccc4[nH]3)cccc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.66
RAB9A P51151 11/20 0.66
ALDH1A1 P00352 9/20 0.66
KDM4E B2RXH2 8/20 0.66
HPGD P15428 8/20 0.66
HSD17B10 Q99714 5/20 0.66
MAPK1 P28482 1/20 0.66
SMN1; SMN2 Q16637 8/20 0.62
NPSR1 Q6W5P4 4/20 0.62
PKM P14618 3/20 0.62
TP53 P04637 2/20 0.62
ABCB11 O95342 1/20 0.62
MAPT P10636 3/20 0.62
GAA P10253 3/20 0.62
HTT P42858 2/20 0.62
GLA P06280 2/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
GPR55 Q9Y2T6 1/20 0.62
F7 P08709 1/20 0.58
LMNA P02545 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29825055 1.00 NPC1 (0.66) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL31677102 1.00 NPC1 (0.66) NPC1RAB9AALDH1A1KDM4EHPGD
Benzene SCHEMBL29179821 0.98 RAB9A (0.64) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL28116783 0.94 NPC1 (0.72) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL27824963 0.92 RAB9A (0.60) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL27844044 0.87 RAB9A (0.55) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL11857261 0.85 NPC1 (0.76) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL227743 0.85 NPC1 (0.78) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL27735312 0.83 RAB9A (0.55) NPC1RAB9AALDH1A1KDM4EHPGD
SCHEMBL8566063 0.82 ALDH1A1 (0.50) NPC1RAB9AALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117317188-B Low-temperature-resistant lithium ion battery containing active carbon negative electrode material and preparation method thereof 湖北美赛尔科技有限公司 2024-03-22 CN claimed
CN-117317188-A Low-temperature-resistant lithium ion battery containing active carbon negative electrode material and preparation method thereof 湖北美赛尔科技有限公司 2023-12-29 CN claimed
CN-111455361-A Surface treatment agent and metal surface treatment method 惠州市瑞翔丰科技有限公司 2020-07-28 CN claimed
US-4057425-A SILVER HALIDE EMULSION POLAROID CORPORATION (US) 1977-11-08 US claimed
JP-7330738-A None JP disclosed
CN-119503795-A Modified activated carbon, silicon-carbon composite material, preparation method thereof, pole piece, application and electrochemical device 上海杉杉新材料有限公司 2025-02-25 CN disclosed
CN-119463287-A Porous polybenzimidazole reinforced polyphenylene sulfide composite membrane for alkaline water electrolysis hydrogen production and preparation method thereof 烟台大学 2025-02-18 CN disclosed
CN-117317188-B Low-temperature-resistant lithium ion battery containing active carbon negative electrode material and preparation method thereof 湖北美赛尔科技有限公司 2024-03-22 CN disclosed
CN-117317188-A Low-temperature-resistant lithium ion battery containing active carbon negative electrode material and preparation method thereof 湖北美赛尔科技有限公司 2023-12-29 CN disclosed
CN-117263868-A Method for synthesizing 2-substituted benzimidazole by nano copper-zinc alloy catalysis 武汉纺织大学 2023-12-22 CN disclosed
US-20230312612-A1 HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2023-10-05 US disclosed
US-20230312612-A1 HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2023-10-05 US disclosed
US-7160854-B2 Binaphthyl peptidomimetics for treating vancomycin resistant Staphylococcus aureas infections UNIVERSITY OF WOLLONGONG (AU) 2007-01-09 US disclosed
US-20050043509-A1 Peptoid compounds UNIVERSITY OF WOLLONGONG 2005-02-24 US disclosed
EP-1412336-A1 PEPTOID COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2004-04-28 EP disclosed
WO-2003002545-A1 PEPTOID COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2003-01-09 WO disclosed
JP-2000154236-A EPOXY RESIN COMPOSITION SHIKOKU CHEM CORP 2000-06-06 JP disclosed
EP-0818562-A1 Composition for treating copper and copper alloy surfaces and method for the surface treatment MEC CO., Ltd. (JP) 1998-01-14 EP disclosed
US-5496590-A Composition for treating copper and copper alloy surfaces and method for the surface treatment MEC CO., LTD. (JP) 1996-03-05 US disclosed
JP-H07330738-A PROTECTING AGENT FOR METAL SURFACE AND PRODUCTION USING THE SAME YAMAGUCHI HIDEAKI 1995-12-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043509-A1 Peptoid compounds VIP, FPR1, VIPR1 NPC1 695/4885RAB9A 4077/4885ALDH1A1 4540/4885
US-20230312612-A1 HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES DDT, EED, CTCF NPC1 4068/4885RAB9A 3506/4885ALDH1A1 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.