SCHEMBL186872

SCHEMBL186872

c1ccc2c(-c3nnc(-c4cccc5ccccc45)[nH]3)cccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 1/20 0.49
PI4K2B Q8TCG2 1/20 0.49
PI4K2A Q9BTU6 1/20 0.49
PI4KB Q9UBF8 1/20 0.49
NISCH Q9Y2I1 1/20 0.46
GSK3B P49841 1/20 0.45
CDK5 Q00535 1/20 0.45
CDK5R1 Q15078 1/20 0.45
BCHE P06276 1/20 0.44
MAPK13 O15264 1/20 0.43
GCGR P47871 1/20 0.43
MAPK12 P53778 1/20 0.43
MAPK11 Q15759 1/20 0.43
MAPK14 Q16539 1/20 0.43
KDM4E B2RXH2 5/20 0.43
ALPL P05186 1/20 0.43
GAA P10253 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24317556 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL415342 0.87 KDM4E (0.46) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL5636467 0.87 PI4KA (0.43) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL28898889 0.84 L3MBTL1 (0.44) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL12110571 0.82 MAPK14 (0.40) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL416819 0.81 TNKS (0.50) MAPK13GCGRMAPK12MAPK11MAPK14
SCHEMBL1250423 0.76 KDM4E (0.42) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL4386837 0.76 NISCH (0.41) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL11828539 0.76 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBNISCH
SCHEMBL25302086 0.75 ALDH1A1 (0.59) NISCHKDM4EALPLGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240334821-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2024-10-03 US disclosed
US-11968893-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2024-04-23 US disclosed
US-20220216422-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2022-07-07 US disclosed
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2022-05-31 US disclosed
US-11289658-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2022-03-29 US disclosed
EP-2315502-B1 Electroluminescent device UDC IRELAND LTD (IE) 2020-10-14 EP disclosed
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same KYULUX, INC. (JP) 2019-10-22 US disclosed
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-08-01 US disclosed
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-06-13 US disclosed
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2019-06-04 US disclosed
EP-1061112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-20 EP disclosed
US-6150042-A ELECTROLUMINESCENCE DEVICE WITH HOLE INJECTING MATERIAL HAVING GOOD DURABILITY BEING A TRIPHENYLENE STRUCTURE OF GIVEN FORMULA HAVING MULTIPLE ETHER, SULFIDE, AND/OR AMINE SUBSTITUTIONS TOYO INK MANUFACTURING CO., LTD. (JP) 2000-11-21 US disclosed
EP-0965629-A1 Compound for organic electroluminescence device and organic electroluminescence device TOYO INK MFG. CO., LTD. (JP) 1999-12-22 EP disclosed
EP-0934992-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1999-08-11 EP disclosed
EP-0866110-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-23 EP disclosed
US-5811834-A Light-emitting material for organo-electroluminescence device and organo-electroluminescence device for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-22 US disclosed
EP-0847228-A2 Material for organoelectroluminescence device and use thereof TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-10 EP disclosed
US-5759444-A FLAT LIGHT SOURCE OR DISPLAY; BRIGHTNESS, STABILITY TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-02 US disclosed
EP-0786926-A2 Light-emitting material for organo-electroluminescence device and organo-electroluminescence devive for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-07-30 EP disclosed
EP-0765106-A2 Light-emitting material for organic electroluminescence device, and organic electroluminescence device for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240334821-A1 Electroluminescent Device PNPO, ODC1, AXL PI4KA 4053/4885PI4K2B 4035/4885PI4K2A 4180/4885
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same TYR, OCIAD2, MAOA PI4KA 2405/4885PI4K2B 2072/4885PI4K2A 1656/4885
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, LEF1, EFNA1 PI4KA 2635/4885PI4K2B 2077/4885PI4K2A 2408/4885
US-11289658-B2 Electroluminescent device PNPO, ODC1, AXL PI4KA 4053/4885PI4K2B 4035/4885PI4K2A 4180/4885
US-20220216422-A1 Electroluminescent Device PNPO, ODC1, AXL PI4KA 4053/4885PI4K2B 4035/4885PI4K2A 4180/4885
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same HNRNPF, RABL6, SRSF6 PI4KA 4658/4885PI4K2B 4659/4885PI4K2A 4719/4885
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element TYR, LEF1, EFNA1 PI4KA 2635/4885PI4K2B 2077/4885PI4K2A 2408/4885
US-11968893-B2 Electroluminescent device PNPO, ODC1, AXL PI4KA 4053/4885PI4K2B 4035/4885PI4K2A 4180/4885
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME TYR, NLRP1, NLRP3 PI4KA 2607/4885PI4K2B 2195/4885PI4K2A 1931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.