Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066761 | 1.00 | MET (0.51) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL22712827 | 1.00 | MET (0.51) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL21301989 | 0.94 | MET (0.48) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL30516385 | 0.94 | MET (0.48) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL30516373 | 0.90 | MET (0.48) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL21302002 | 0.90 | MET (0.48) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL31066775 | 0.90 | MET (0.48) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL3853031 | 0.90 | ACHE (0.55) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL21301976 | 0.90 | MET (0.48) | METLMNAALDH1A1MAPTACHE | |
| SCHEMBL31066776 | 0.90 | MET (0.48) | METLMNAALDH1A1MAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041300-B | Indole and benzimidazole derivatives as dual 5-HT2A and 5-HT6 receptor antagonists | 阿达梅德制药公司 | 2023-07-28 | — | — | CN | disclosed |