Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215693 | 1.00 | OPRK1 (0.45) | OPRK1P2RY12SCN10AMAPTCRBN | |
| SCHEMBL30516619 | 0.90 | OPRK1 (0.45) | OPRK1P2RY12SCN10AMAPTCRBN | |
| SCHEMBL24215455 | 0.90 | OPRK1 (0.45) | OPRK1P2RY12SCN10AMAPTCRBN | |
| SCHEMBL4131161 | 0.87 | OPRK1 (0.51) | OPRK1P2RY12MAPTHDAC6NPC1 | |
| SCHEMBL24213973 | 0.86 | OPRK1 (0.43) | OPRK1P2RY12MAPTCRBNDDB1 | |
| SCHEMBL23167379 | 0.85 | ALDH1A1 (0.52) | OPRK1P2RY12MAPTCYP3A4CYP2C19 | |
| SCHEMBL29779622 | 0.85 | ALDH1A1 (0.52) | OPRK1P2RY12MAPTCYP3A4CYP2C19 | |
| SCHEMBL29779599 | 0.84 | P2RY12 (0.47) | OPRK1P2RY12MAPTHDAC6NPC1 | |
| SCHEMBL23166436 | 0.84 | P2RY12 (0.47) | OPRK1P2RY12MAPTHDAC6NPC1 | |
| SCHEMBL24215439 | 0.84 | HDAC6 (0.39) | SCN10ACYP3A4FFAR4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |