Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516657 | 0.77 | TSHR (0.52) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL12181432 | 0.75 | RAB9A (0.90) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL30516645 | 0.75 | NAMPT (0.39) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL825926 | 0.75 | RAB9A (0.84) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL30516651 | 0.74 | HDAC1 (0.50) | RAB9ANPC1HPGDHDAC1 | |
| SCHEMBL12181229 | 0.74 | RAB9A (1.00) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL3456092 | 0.74 | RAB9A (1.00) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL30516656 | 0.74 | TSHR (0.49) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL27876089 | 0.71 | RAB9A (0.66) | TSHRHSD17B10RAB9ANPC1HPGD | |
| SCHEMBL1279114 | 0.70 | RAB9A (0.69) | TSHRHSD17B10RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |