Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516632 | 0.76 | CNR2 (0.36) | NAMPTPTGDRHPGDNPC1RAB9A | |
| SCHEMBL30516660 | 0.75 | TSHR (0.60) | HPGDNPC1RAB9AATMTAS1R3 | |
| SCHEMBL30516670 | 0.73 | NPC1 (0.49) | HPGDNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL30516651 | 0.72 | HDAC1 (0.50) | PTGDRHPGDNPC1RAB9A | |
| SCHEMBL31438387 | 0.72 | NAMPT (0.40) | NAMPTHPGDGRM1 | |
| SCHEMBL31001168 | 0.72 | NAMPT (0.40) | NAMPTHPGDGRM1 | |
| SCHEMBL31438405 | 0.69 | TLR7 (0.42) | — | |
| SCHEMBL4774133 | 0.67 | MAPK10 (0.51) | NAMPTHPGDNPC1RAB9ALMNA | |
| SCHEMBL31203422 | 0.67 | KEAP1 (0.47) | HPGDNPC1RAB9ALMNAMAPK1 | |
| SCHEMBL25607337 | 0.66 | NAMPT (0.48) | NAMPTHPGDNPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |