Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478646 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL26401595 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL30402800 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL26401575 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL3777362 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL2521491 | 0.82 | HPGD (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL28029191 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL16836610 | 0.81 | SLC6A3 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL29091643 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL2713939 | 0.80 | MAPT (0.44) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601149-A | Aminoquinazoline derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-15 | — | — | CN | disclosed |