SCHEMBL30516783

SCHEMBL30516783

Oc1ccc2c(c1)CCc1c(-c3ccccc3)c[nH]c1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
CYP26A1 O43174 4/20 0.45
ALOX5 P09917 1/20 0.45
S1PR1 P21453 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
ESR2 Q92731 2/20 0.41
MIF P14174 4/20 0.41
MAOB P27338 1/20 0.41
ESR1 P03372 2/20 0.40
NTRK1 P04629 1/20 0.39
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
CCNA1 P78396 1/20 0.39
CHEK1 O14757 1/20 0.37
CLK1 P49759 1/20 0.37
CLK2 P49760 1/20 0.37
CLK3 P49761 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30149529 0.80 ACHE (0.46) CA1CA2CA4CA6MIF
SCHEMBL5809047 0.80 ACHE (0.46) CA1CA2CA4CA6MIF
SCHEMBL29051548 0.73 CYP1A2 (0.34) S1PR1CA1CLK1
SCHEMBL14848740 0.72 PTPN1 (0.46) MAOBESR1NTRK1CDK2CHEK1
SCHEMBL29899282 0.70 EGFR (0.52) CA1CA2CA4CA6CLK1
SCHEMBL5814304 0.70 EGFR (0.52) CA1CA2CA4CA6CLK1
SCHEMBL8047659 0.70 NR1H2 (0.55) HSP90AA1CYP26A1ALOX5CA1CA2
SCHEMBL28462071 0.69 PARP1 (0.40)
SCHEMBL784291 0.68 MAOB (0.59) HSP90AA1CYP26A1ESR2MIFMAOB
SCHEMBL8460792 0.67 SRD5A1 (0.56) HSP90AA1CYP26A1MIFMAOBNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535429-A Amino acid modified BODIPY compound and preparation method and application thereof 复旦大学 2023-08-04 CN disclosed