SCHEMBL14848740

SCHEMBL14848740

CCCCCCCOc1ccc2c(c1)CCc1c(-c3ccccc3)c[nH]c1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.46
PTPN11 Q06124 5/20 0.45
THRA P10827 2/20 0.43
THRB P10828 2/20 0.43
CDC7 O00311 1/20 0.40
PLK4 O00444 1/20 0.40
CHEK1 O14757 1/20 0.40
CHUK O15111 1/20 0.40
PDPK1 O15530 1/20 0.40
DYRK3 O43781 1/20 0.40
ROCK2 O75116 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
PAK4 O96013 1/20 0.40
NTRK1 P04629 1/20 0.40
PRKCG P05129 1/20 0.40
INSR P06213 1/20 0.40
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
CDK1 P06493 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30149529 0.81 ACHE (0.46) ESR1ACHE
SCHEMBL29051548 0.75 CYP1A2 (0.34) MAPK1DYRK1AACHE
SCHEMBL5057429 0.74 PTPN1 (0.61) PTPN1PTPN11HDAC8SOAT1LTA4H
SCHEMBL29899282 0.74 EGFR (0.52)
SCHEMBL30516783 0.72 HSP90AA1 (0.46) CHEK1NTRK1CDK2CLK2MAOB
SCHEMBL8719339 0.72 THRA (0.47) PTPN1PTPN11THRATHRBPDK2
SCHEMBL15574397 0.72 PTPN11 (0.56) PTPN1PTPN11THRATHRBHDAC8
SCHEMBL7941538 0.72 PTPN11 (0.59) PTPN1PTPN11HDAC8SOAT1LTA4H
SCHEMBL17388694 0.72 PTPN11 (0.59) PTPN1PTPN11HDAC8SOAT1LTA4H
SCHEMBL9850396 0.71 PTPN11 (0.58) PTPN1PTPN11HDAC8SOAT1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130087741-A1 INK HAVING POLYVINYL ACETAL BINDER KODAK PHILIPPINES LTD. 2013-04-11 US disclosed
US-20130089713-A1 ARTICLE PRINTED WITH INFRARED DYE KODAK REALTY INC. 2013-04-11 US disclosed
US-20130089713-A1 ARTICLE PRINTED WITH INFRARED DYE KODAK REALTY INC. 2013-04-11 US disclosed
US-20130087740-A1 INFRARED FLUORESCENT COMPOSITION HAVING POLYVINYL ACETAL BINDER FPC INC. 2013-04-11 US disclosed
US-20130087741-A1 INK HAVING POLYVINYL ACETAL BINDER KODAK PHILIPPINES LTD. 2013-04-11 US disclosed
US-20130087740-A1 INFRARED FLUORESCENT COMPOSITION HAVING POLYVINYL ACETAL BINDER FPC INC. 2013-04-11 US disclosed