Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516844 | 0.85 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1CASP1CASP7 | |
| SCHEMBL30416847 | 0.84 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL9461754 | 0.71 | ALDH1A1 (0.56) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL11635317 | 0.69 | CYP1A2 (0.51) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL30416389 | 0.69 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1CASP1CASP7 | |
| SCHEMBL30416015 | 0.69 | ALDH1A1 (0.42) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL30416506 | 0.69 | POLB (0.54) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4790004 | 0.68 | POLB (0.49) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL15651285 | 0.68 | HRH3 (0.53) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL30415191 | 0.67 | HDAC6 (0.44) | CYP2C9CYP2C19AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088477-A1 | MULTIFUNCTIONAL COMPOUND CAPABLE OF DEGRADING BTK KINASE, AND COMPOSITION AND USE | 杭州和正医药有限公司 | 2023-05-25 | — | — | WO | disclosed |