Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | C5 | P01031 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745903 | 0.85 | TSHR (0.54) | TSHRHTR2AHTR2CHTR2BPTGS2 | |
| SCHEMBL7674211 | 0.85 | TSHR (0.42) | TSHRHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL2110334 | 0.83 | TP53 (0.47) | TSHRHTR2AHTR2CHTR2BPTGS2 | |
| SCHEMBL31276823 | 0.83 | TP53 (0.47) | TSHRHTR2AHTR2CHTR2BPTGS2 | |
| SCHEMBL6591473 | 0.81 | PTGS2 (0.57) | TSHRHTR2AHTR2CHTR2BPTGS2 | |
| SCHEMBL7152600 | 0.81 | LMNA (0.44) | TSHRHTR2BPTGS2MEN1KMT2A | |
| SCHEMBL7146617 | 0.81 | LMNA (0.44) | TSHRHTR2BPTGS2MEN1KMT2A | |
| SCHEMBL3670597 | 0.81 | LMNA (0.44) | TSHRHTR2BPTGS2MEN1KMT2A | |
| SCHEMBL11091003 | 0.80 | HTR2A (0.45) | TSHRHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL5227815 | 0.80 | PTGS2 (0.42) | TSHRHTR2AHTR2CHTR2BPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222326-A1 | New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders | UCB PHARMA, S.A. (BE) | 2010-09-02 | — | — | US | claimed |
| CN-101851244-B | Substituted phenyl keto enols as pesticides and herbicides | BAYER AG | 2013-08-21 | — | — | CN | disclosed |
| CN-101851244-A | The phenyl keto-enol pesticide and the weedicide that replace | BAYER AG | 2010-10-06 | — | — | CN | disclosed |
| US-20100222326-A1 | New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders | UCB PHARMA, S.A. (BE) | 2010-09-02 | — | — | US | disclosed |
| CN-101580465-A | Substituted phenyl keto enols as pesticides and herbicides | BAYER AG (DE) | 2009-11-18 | — | — | CN | disclosed |
| CN-101575312-A | Substituted phenyl keto enols as pesticides and herbicides | BAYER AG (DE) | 2009-11-11 | — | — | CN | disclosed |
| CN-1631879-A | Substituted phenyl keto enols as pesticides and herbicides | BAYER AG (DE) | 2005-06-29 | — | — | CN | disclosed |
| CN-1535956-A | Substituted phenyl keto-enol pesticide and weedicide | — | 2004-10-13 | — | — | CN | disclosed |
| CN-1215390-A | Substituted phenyl ketoenol pesticides and herbicides | BAYER AG (DE) | 1999-04-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222326-A1 | New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders | CNR2, CNR1, SLC18A2 | TSHR 1696/4885HTR2A 33/4885HTR2C 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.