Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803011 | 1.00 | IGF1R (0.67) | IGF1RRAB9ANPC1HTTMAPT | |
| SCHEMBL10803006 | 1.00 | IGF1R (0.67) | IGF1RRAB9ANPC1HTTMAPT | |
| SCHEMBL10805360 | 0.81 | PIM1 (0.67) | IGF1RRAB9ANPC1HTTMAPT | |
| SCHEMBL10805356 | 0.81 | PIM1 (0.67) | IGF1RRAB9ANPC1HTTMAPT | |
| SCHEMBL30990562 | 0.80 | IGF1R (1.00) | IGF1RMAPTPTP4A3CRHBPCRHR2 | |
| SCHEMBL1249000 | 0.80 | IGF1R (1.00) | IGF1RMAPTPTP4A3CRHBPCRHR2 | |
| SCHEMBL1249001 | 0.80 | IGF1R (1.00) | IGF1RMAPTPTP4A3CRHBPCRHR2 | |
| SCHEMBL12204299 | 0.78 | PTP4A3 (0.79) | IGF1RHTTMAPTMEN1KMT2A | |
| SCHEMBL20535130 | 0.78 | PTP4A3 (0.79) | IGF1RHTTMAPTMEN1KMT2A | |
| SCHEMBL20535128 | 0.78 | PTP4A3 (0.79) | IGF1RHTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286934-A1 | Use of Multi-Kinase Inhibitors to Treat RNA Virus Infections | ICAHN SCHOOL MED MOUNT SINAI (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286934-A1 | Use of Multi-Kinase Inhibitors to Treat RNA Virus Infections | EIF2AK2, SARS1, ACE2 | IGF1R 2284/4885RAB9A 1744/4885NPC1 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.