Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 1.00 |
| ▸ | PIM1 | P11309 | 3/20 | 0.66 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | INSR | P06213 | 1/20 | 0.59 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249000 | 1.00 | IGF1R (1.00) | IGF1RPIM1PIM2HPGDINSR | |
| SCHEMBL1249001 | 1.00 | IGF1R (1.00) | IGF1RPIM1PIM2HPGDINSR | |
| SCHEMBL20637585 | 0.85 | TDP1 (0.74) | IGF1RHPGDKDM4ENSD2POLB | |
| SCHEMBL20535128 | 0.85 | PTP4A3 (0.79) | IGF1RPIM1PTP4A3CRHBPCRHR2 | |
| SCHEMBL20535130 | 0.85 | PTP4A3 (0.79) | IGF1RPIM1PTP4A3CRHBPCRHR2 | |
| SCHEMBL12204299 | 0.85 | PTP4A3 (0.79) | IGF1RPIM1PTP4A3CRHBPCRHR2 | |
| SCHEMBL19119969 | 0.85 | TDP1 (0.74) | IGF1RHPGDKDM4ENSD2POLB | |
| SCHEMBL1247522 | 0.81 | PIM1 (0.72) | IGF1RPIM1PIM2HPGDPOLB | |
| SCHEMBL1247523 | 0.81 | PIM1 (0.72) | IGF1RPIM1PIM2HPGDPOLB | |
| SCHEMBL30520063 | 0.80 | IGF1R (0.67) | IGF1RPIM1HPGDPTP4A3CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108785-A | 5 Alpha, 8 alpha-peroxy ergosterol-3-thiazolidinedione derivative, and preparation method and application thereof | 齐齐哈尔医学院 | 2024-05-31 | — | — | CN | disclosed |