SCHEMBL3052007

SCHEMBL3052007

O=C(Cc1cccc2ccccc12)Oc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.78
TDP1 Q9NUW8 2/20 0.78
SIRT5 Q9NXA8 1/20 0.74
MAPT P10636 1/20 0.56
CYP1A2 P05177 2/20 0.51
ATM Q13315 1/20 0.50
LMNA P02545 3/20 0.49
PKM P14618 1/20 0.49
CYP19A1 P11511 1/20 0.49
CYP3A4 P08684 2/20 0.48
CYP2C19 P33261 2/20 0.48
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
RECQL P46063 1/20 0.48
HPGD P15428 1/20 0.48
PTGER4 P35408 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11858636 0.85 L3MBTL1 (0.63) L3MBTL1TDP1SIRT5MAPTCYP1A2
SCHEMBL5888866 0.83 L3MBTL1 (0.78) L3MBTL1TDP1SIRT5CYP1A2ATM
SCHEMBL590845 0.82 TDP1 (0.67) L3MBTL1TDP1SIRT5MAPTCYP1A2
SCHEMBL28818018 0.81 L3MBTL1 (0.65) L3MBTL1TDP1SIRT5MAPTCYP1A2
Ammonia Solution, Strong SCHEMBL21246670 0.81 TDP1 (0.65) L3MBTL1TDP1SIRT5MAPTCYP1A2
SCHEMBL709403 0.79 L3MBTL1 (0.68) L3MBTL1TDP1SIRT5CYP1A2ATM
SCHEMBL21693922 0.79 TDP1 (0.62) L3MBTL1TDP1SIRT5MAPTCYP1A2
SCHEMBL29503119 0.79 L3MBTL1 (0.68) L3MBTL1TDP1SIRT5CYP1A2ATM
SCHEMBL13222634 0.79 L3MBTL1 (0.67) L3MBTL1TDP1SIRT5MAPTCYP1A2
SCHEMBL11429994 0.79 CYP19A1 (0.54) L3MBTL1TDP1SIRT5MAPTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8647878-B2 Highly refractive immersion liquids and their use CARL ZEISS AG (DE) 2014-02-11 US disclosed
US-8647878-B2 Highly refractive immersion liquids and their use CARL ZEISS AG (DE) 2014-02-11 US disclosed
US-8647878-B2 Highly refractive immersion liquids and their use CARL ZEISS AG (DE) 2014-02-11 US disclosed
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use CARL ZEISS AG (DE) 2010-08-26 US disclosed
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use CARL ZEISS AG (DE) 2010-08-26 US disclosed
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use CARL ZEISS AG (DE) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use NR4A3, NR2E3, NR4A1 L3MBTL1 2996/4885TDP1 4272/4885SIRT5 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.