Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL21246670

N.N.O=C(Cc1cccc2ccccc12)OC(=O)Cc1cccc2ccccc12

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.65
L3MBTL1 Q9Y468 6/20 0.60
SIRT5 Q9NXA8 1/20 0.57
ATM Q13315 1/20 0.54
PKM P14618 2/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 2/20 0.51
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51
KDM4E B2RXH2 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.49
ACP3 P15309 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL590845 0.98 TDP1 (0.67) TDP1L3MBTL1SIRT5ATMPKM
SCHEMBL590846 0.88 SIRT5 (0.61) TDP1L3MBTL1SIRT5ATMPKM
Ammonia Solution, Strong SCHEMBL28218537 0.86 L3MBTL1 (0.66) TDP1L3MBTL1SIRT5ATMPKM
Ammonia Solution, Strong SCHEMBL28044090 0.86 L3MBTL1 (0.66) TDP1L3MBTL1SIRT5ATMPKM
SCHEMBL28818018 0.85 L3MBTL1 (0.65) TDP1L3MBTL1SIRT5ATMPKM
Acetic Acid SCHEMBL29007541 0.85 TDP1 (0.60) TDP1L3MBTL1SIRT5ATMPKM
SCHEMBL8920397 0.85 ALDH1A1 (0.59) TDP1L3MBTL1SIRT5LMNACYP1A2
SCHEMBL2678995 0.84 TDP1 (0.54) TDP1L3MBTL1SIRT5ATMPKM
SCHEMBL29503119 0.84 L3MBTL1 (0.68) TDP1L3MBTL1SIRT5ATMPKM
SCHEMBL21693922 0.84 TDP1 (0.62) TDP1L3MBTL1SIRT5ATMPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749626-A1 SMART RELEASE POTASH FERTILIZER GRANULES Rynan Technologies Pte. Ltd. (SG) 2020-12-16 EP disclosed
WO-2019153078-A1 SMART RELEASE POTASH FERTILIZER GRANULES RYNAN TECHNOLOGIES PTE LTD (SG) 2019-08-15 WO disclosed