Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | LTA4H | P09960 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19198714 | 1.00 | RAB9A (0.69) | RAB9ALTA4HHDAC1HDAC8HDAC6 | |
| SCHEMBL4805011 | 0.90 | LTA4H (0.79) | RAB9ALTA4HCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10054992 | 0.89 | RAB9A (0.83) | RAB9ALTA4HHDAC1HDAC8HDAC6 | |
| SCHEMBL19198137 | 0.83 | RAB9A (0.63) | RAB9ALTA4HKDM4CLMNANPC1 | |
| SCHEMBL30520217 | 0.83 | RAB9A (0.63) | RAB9ALTA4HKDM4CLMNANPC1 | |
| SCHEMBL4024922 | 0.82 | MAPKAPK2 (0.61) | RAB9ALTA4HKDM4CKDM5BLMNA | |
| SCHEMBL9798992 | 0.82 | FFAR1 (0.68) | RAB9AHDAC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10559761 | 0.81 | RAB9A (0.71) | RAB9ALTA4HHDAC1HDAC8HDAC6 | |
| SCHEMBL7246616 | 0.81 | RAB9A (0.71) | RAB9ALTA4HHDAC1HDAC8HDAC6 | |
| SCHEMBL19198628 | 0.81 | RAB9A (1.00) | RAB9ALTA4HHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM5A, KDM1A | RAB9A 3032/4885LTA4H 2790/4885HDAC1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.